I have in the past and have asked to be taken off of those meds and switched to others without sexual side effects.

I know some can but I've never been on any.

It totally depends on your body chemistry. Certain antidepressants will do that to some people, but not other people. SSRIs are especially prone to messing with not only libidos, but also sexual responses (difficulty getting and maintaining erections for men, difficulty becoming lubricated for women, and difficulty reaching orgasm for both genders). But again, it won't do that for all people.

It's not psychosomatic at all, but I'm really glad it isn't something you've had to deal with!

They can. I've used them in the past and they didn't have much effect on me, sexually or otherwise.

They did for me. I'm glad I'm now self-medicating...as in I know what to do to power through a depression.

It can. We're all made different and affected differently by medications. Some meds can interfere and others may not. I have had it happen but it's nothing a little foreplay can't help. Mine more affected my body's natural lubrication which isn't that big of deal, I just grab a bottle. I'd rather have vaginal dryness than not have the medication. I really don't think I even need it anymore and it's more of a fear of going off and withdrawal symptoms of it but I'm prepared to do so within the next few years so that I can get pregnant and not have those chemicals messing with my child while he/she is growing.

I took wellbutrin once..I found my mind was still as much into sex, but I was maybe less dependent on it and it took a little longer to get things going, so to speak and maybe a slightly numbish feeling when I had sex...meaning like having sex with a condom vs. nothing on. Hard to describe. Less sensation, more work to orgasm. I'm no sure if any of it was mental or not, because I was told of the possible side effects. I took that one vs others, to avoid a big effect.

Depends on the medication

They definitely can. I had huge issues with the medication I used to be on.

The side effects of a medication vary widely and depend on the person taking them. Antidepressants are generally known, as a group, to contribute to a decreased sex drive, though there are cases of idiosyncratic effects where people experience the opposite. Furthermore, if interest in sexual activity was decreased due to a depressed mood, lack of energy and other symptoms, alleviation of these symptoms may lead to increase desire for sexual activity.

A friend of mine was taking two medications; a commonly prescribed antidepressant and an adjunct, which is typically marketed as an antipsychotic, but has off-label uses for boosting the antidepressant action of other drugs. He felt, in his words, "pretty much asexual", though he meant it in terms of libido and interest rather than a change in sexual orientation.

In my own case, I have felt mildly depressed in the past, and I wanted to avoid commercial antidepressants since it wasn't terribly severe. I have used St. John's Wort extensively in the past, and it helped my mood to a degree (I realize doing this without the supervision of a physician was not the best of ideas). What I didn't notice until I stopped taking it (just a month ago) was that my interest in sexual activity seemed to diminish, lower and lower until I had almost no interest at all. That's just a personal experience, though, and it was with an herbal supplement rather than a pharmaceutical antidepressant.

for me it doesnt.

My girlfriend was taking some for a while. And while it made her less hot-headed (she tends to get really snappy when upset or depressed), what little of a sex drive she had went totally out the window.

However, she stopped taking it because it was upsetting me that we couldn't even have sex anymore or even play around without her feeling totally numb to it.

I have been on them in the past and found that it didn't kill my sex drive but made it harder for me to get wet and made it harder for me to get off!